A 17-year-old female asked:
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why do patients with hereditary spherocytosis have fatigabilty?

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Dr. Alan Weitberg
45 years experience Hematology and Oncology
See below: The red blood cells in people with hereditary spherocytosis are sphere-shaped rather than the disk shape of a normal red blood cell. These spherocytes are destroyed in the spleen ( which is often enlarged), resulting in varying degrees of anemia. It predominantly is the anemia which causes fatigue. This is a common symptom in this disease.
Answered on Jul 18, 2014
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