A 28-year-old male asked:
what do i do for hereditary spherocytosis?
2 doctor answers
Dr. Robert Kwok answered
33 years experience Pediatrics
See a hematologist: Most children have mild disease, can live a normal life, and do not require splenectomy. Take Folic Acid supplements as recommended. Watch for sudden anemia crises, which may be from parvovirus b19 (fifth disease). Splenectomy (spleen removal) is for those with severe disease or who develop symptomatic gallstones (gall bladder removal can be performed at the same time). Be sure to get vaccinated.
Answered on Jun 25, 2014
Dr. Michael Engel answered
20 years experience Pediatric Hematology and Oncology
It depends on the...: Severity of your disease. There is wide variation in the clinical presentation, even within the same family (presumably the same mutation). This is because of the influence of "modifier" loci. Hs cells are more fragile as they pass through the circulation. The bone marrow works harder to compensate. Pts are at risk for hemolytic and aplastic crises. Take folate (folic acid) supplement. Be eval'd 4 abd pain.
Answered on Nov 15, 2018
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