A member asked:

What happens when you mix percodan (oxycodone and aspirin) with meth?

4 doctors weighed in across 2 answers

Don't mix: First of all, nobody should take methamphetamine as it is dangerous and illegal. Meth can cause neurological damage as well as damage the heart, cause strokes, and death. Percodan (oxycodone and aspirin) is an opiate and can suppress the brain's signals that tell us to breathe. Overdose with an opiate can lead to death from respiatory arrest. Meth + Percodan (oxycodone and aspirin) may have some drug interactions that are unknown/ unstudied.

Answered 7/16/2020

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Dr. Vasu Brown answered

Specializes in Integrative Medicine

Heart stress: Puts tremendous strain on the heart generates confusion in the central nervous system poses a greater risk of a drug overdose poses tremendous risk for repeated use or addiction to a dangerous practice.

Answered 9/28/2020

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