A member asked:

Can one's body develop a resistance to benadryl (diphenhydramine) if one takes it on a daily basis? will the medicine eventually lose it's effectiveness as time passes?

A doctor has provided 1 answer

Yes: All antihistamines can lose effectiveness. Most are over the counter now and i'd recommend switching to another family like allegra, claritin, (loratadine) or tavist.

Answered 11/28/2017

5.9k views

Thank

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