50 mg total: You can take a total of 50 mg up to every 4 hours. I've never heard of extra strength Benadryl (diphenhydramine) (they do make a 50 mg tablet, but i've always seen it behind the counter at a pharmacy). All the over-the-counter strengths i've ever seen are 25 mg, so you can take 2 of those.
Answered 1/13/2015
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