A 45-year-old member asked:
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what are the side effects of demerol (meperidine hydrochloride) use, abuse?

2 doctor answers
Dr. Einar Ottestad
18 years experience Pain Management
Many: Opioids cause sedation, nausea, itchiness, constipation, respiratory depression, and death in large doses when not tolerant. Meperidine is unique in that its metabolite, normeperidine, can accumulate and cause neuroexcitation and seizures, especially in patients with kidney problems.
Answered on Sep 28, 2016
Dr. David Rosenfeld
26 years experience Pain Management
Death: Nausea, sedation, seizures and death.
Answered on Oct 3, 2016

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Withdrawal: Immediate and severe withdrawal-nausea, vomitting, severe pain sensations if chronic use. Just waking up otherwise.
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Dr. Mehul Desai
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Maybe: Most commonly an increase in pain particularly if that was the intended use of the demerol (meperidine hydrochloride).
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