A 45-year-old member asked:
what are the side effects of demerol (meperidine hydrochloride) use, abuse?
2 doctor answers
Dr. Einar Ottestad answered
18 years experience Pain Management
Many: Opioids cause sedation, nausea, itchiness, constipation, respiratory depression, and death in large doses when not tolerant. Meperidine is unique in that its metabolite, normeperidine, can accumulate and cause neuroexcitation and seizures, especially in patients with kidney problems.
Answered on Sep 28, 2016
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