A member asked:

Why is it advised to be careful with grapefruit on some meds like clonazepam and paxil (paroxetine) too i think?

A doctor has provided 1 answer
Dr. Amanda Patsfield answered

Specializes in Pharmacology

Drug food interacts: Grapefruits utilize the same metabolic pathway that some medications use. This isoenzyme is located in your gut. If the grapefruit is occupying the enzyme, the drug can not be effectively metabolized. The drugs levels will rise in the blood stream and side effects are more likely to occur. In the case of clonazepam , increased sedation and cognitive skills can be greatly affected.

Answered 7/3/2014

3.9k views

Thank

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