One of my wife's mosquito bites now resembles a target or bulls-eye. got it last night and she doesn't remember a tick but worried about lyme disease?

Don't be.: The story is not consistent with Lyme disease. The tick has to be attached for at least 12 hours to infect.

Lyme: Since she had some type of bites, it is possible what she thinks is mosquito bites may possibly be something else. It is important to visit a Dermatologist who may be able to provide you a more accurate diagnosis as there are multiple causes for annular erythemas such as Tinea Corporis, Erythema Annulare Centrifigum, Erythema Gyratum Repens, Erythema (Chronicum) Migrans, Granuloma Annulare, etc.