Take 25mg losartan at night but it doesn't last throughout day. still have bp spikes. why? also on betapace (sotalol) 40 mg twice daily for atrial tachycardia.

BP control: Be aware that it is not unusual to be on 2-3 different blood pressure medicines to achieve a good BP control. 75% of North Americans with hypertension take 3 BP meds max dose! And low salt diet is crucial for BP control, so if you are following a low salt diet and still your BP is high, consult your physician to add a second agent (diuretics maybe?).