A member asked:

How long does it lasts the sedative effects of seroquel (quetiapine) once you take it? i'm starting on it before sleep and don't want to have problem waking early

A doctor has provided 1 answer

Dr. Linda Callaghan answered

Specializes in Addiction Medicine

Depends.: The immediate release is 6 hours and the extended release is between 9 to 12 hours. If you take 50 mg. of Seroquel (quetiapine) IR at 10 PM , you have about 25 mg. left at 4 AM.

Dr Khokhar agreed

Answered 8/2/2014

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A member asked:

How long does it lasts the sedative effects of seroquel (quetiapine) once you take it? i'm starting on it before sleep and don't want to have problem waking early

A doctor has provided 1 answer

Dr. Linda Callaghan answered

Dr Khokhar agreed

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