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A 47-year-old member asked:

Can you tell me if methadone comes up as an opiate on drug screens?

1 doctor answer1 doctor weighed in
Dr. Alan Wartenberg
A Verified Doctoranswered
Addiction Medicine 51 years experience
No: An "opiate," by definition, is chemically derived from the opium plant, like morphine and codeine. Methadone is a synthetic chemically unrelated to opiates, but acts at the same receptors - hence, it is called an "opioid." - latin for "like an opiate." Demerol, (meperidine hydrochloride) fentanyl, Darvon and other opioids are also synthetic drugs. Oxycodone, hydromorphone and others are semi-synthetic opiates.
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