A 36-year-old female asked:
can being obese cause an enlarged spleen? i was severely overweight, have fatty liver, but lft's are normal. so the liver seems to be functioning fine, wondering what could cause the spleen issue?
2 doctor answers • 2 doctors weighed in

Dr. Tamara Modilevskyanswered
Internal Medicine 54 years experience
Yes: Non alcoholic fatty liver can cause portal hypertension which is a cause of spleen enlargement. Portal hypertension means that there is increased pressure and abnormal blood flow in portal vein system. Portal vein brings blood to the liver.
4k viewsAnswered >2 years ago

Dr. Raad Jajoanswered
Psychiatry 23 years experience
Many explanations: one most possible cause is portal hypertension, others could hypersplenism due to overdestructions of RBC
4k viewsAnswered >2 years ago
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Last updated May 14, 2019
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