Severe ins resistanc: Severe Insulin resistance (IR) requiring U500 Insulin is more and more common. There are genetic forms of IR (eg. Insulin receptor defects, lipodystrophy), but these are rare. Talk to your endocrinologist. Is there something causing IR (eg. steroids, infection, inflammation). Diet/weight loss is probably the most important factor now.
Answered 6/25/2014
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