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Wyoming, MI
A 28-year-old female asked:

Can topical clindamycin cause constipation? i read it can be linked to colitis, but i have no diarrhea, bleeding or pain. any relation?

2 doctor answers2 doctors weighed in
Dr. Robert Uyeda
General Surgery 46 years experience
It would: be a rare side effect for any topical medication to cause constipation. Clindamycin, typically oral, and other antibiotics can cause C. difficile colitis and resulting diarrhea.
Dr. Stephen Scholand
Infectious Disease 24 years experience
Clindamycin effects: Clindamycin is an antibiotic used 2 fight acne, so topical preparations are used for that. As with any topically applied medicine, there is absorption through the skin. Clindamycin is linked with a side effect known as C. Diff colitis which can be very bad. Constipation however has nothing to do with the med or this side effect. Probably u need to drink more, as the colon reabsorbs water. + Fiber2

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