A member asked:

What is the possible problem for 70 yrs old man with macrocytic anemia. hb 9, retic count .85% , mcv 108. vitamins, liver, kidney, wbc, plat. normal?

A doctor has provided 1 answer

Macrocytic Anemia: Anemia is due to (a) decreased RBC production, (b) increased RBC destruction, and/or (c) blood loss. Macrocytic RBCs and low reticulocyte count suggest decreased RBC production. Common causes: folate def, B12 def, alcohol, liver disease, hypothyroidism. Less common causes: myelodysplastic syndrome, LGL leukemia, acute leukemia, HBV, HCV, HIV. Drugs can cause MA: Hydrea, (hydroxyurea) zidovudine, etc.

Answered 6/24/2014

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