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A member asked:
Could you please describe, in general, the two ways anti-depressant medication works?
A doctor has provided 1 answer
Briefly: 1. SSRI will block reuptake and result in increased Serotonin in the synaptic cleft 2. SNRI will block reuptake and result in increased Norepinephrine and Serotonin in the synaptic cleft 3.This will down regulate the 5HT1A auto receptor which will increase serotonin. This increases the neuronal firing rate and brain activity, increase BDNF, decrease depression.
Answered 4/22/2016
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