Can i take chlorhexidine gluconate oral rinse before sleeping? thanks in advance.

Yes, it's excellent: Yes, you can rinse with the chlorhexidene before going to bed. It's an effective anti-bacterial agent that reduces bacteria in your mouth. Before bed is a great time because you have reduced salivary flow while you sleep and the chlorhexidene sticks around in your mouth for a while after you spit it out.

Recommended: to use after breakfast and before bedtime. The chlorhexidine for long periods can cause a removable stain on the teeth.

Yes but...: I would follow the directions of the dentist whom prescribed the rinse for you.