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A member asked:
Can you tell me how nitrous oxide, sharpies, paint, get people high?
2 doctors weighed in across 2 answers
Nitrous Oxide: From wikipedia: While N2O affects quite a few ion channels, its anaesthetic, hallucinogenic, and euphoriant effects are likely caused predominantly or fully via inhibition of NMDAR-mediated currents. In addition to its effects on ion channels, N2O may act to imitate Nitric Oxide (NO) in the central nervous system, and this may be related to its analgesic and anxiolytic properties. Search web.
Answered 6/30/2014
4k views
Nitrous Oxide : is an anesthetic gas best known for its use in dentistry as a short-term analgesia and anxiolysis. As a mild analgesic, it has an action similar to morphine as it may act on opiate receptors and get you high. Outside of a medical setting, nitrous oxide can be dangerous. With regards to sharpies and paint the mechanism is idiopathic.
Answered 5/29/2014
4k views
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