A member asked:

I've been taking 100mg minocycline for acne for a few years now and for the past few months it has not been working near as well. other options?

A doctor has provided 1 answer

Spironolactone: Acne in adult women is a hormone effect. Usually the hormones are normal (do you have normal menses?). It can be worse in response to progesterones used for birth control. It can be part of PCOS. Only about 10% of such women respond to antibiotics such as minocycline. Most of them love the result from the antiandrogen spironolactone, typically 100mg daily, result in 2-3 months. Safe onless pregnan

Answered 10/4/2016

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