A member asked:

Is gout caused by an error in nucleic acid metabolism that leads to a buildup of uric acid in body fluids?

3 doctors weighed in across 2 answers
Dr. Richard Blake answered

Specializes in Podiatry

Gout Attack Reason: Uric acid that produces gout is a normal breakdown product of purines (nucleic acids) in our bodies.A gout attack is caused by an excessive buildup of uric acid in the blood stream. Daily uric acid is filtered by the kidneys and passed through our urine. Over a certain concentration, the uric acid crystals leave the blood and collect in a susceptible area (like an arthritic big toe joint).

Answered 5/14/2014

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Uric acid: Most commonly, uric acid production is elevated from diet or its excretion is reduced from kidney impairment or diuretic rx. Enzyme defects can also elevate uric acid.

Answered 9/19/2014

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Related Questions

A member asked:

How to prevent gout and lower uric acid in my body?

5 doctors weighed in across 4 answers