Glad you asked!: Aspirin irreversibly binds platelets for the life of the platelet (which is 10 days). Every day, our bodies make new platelets replacing the 10% that is lost. When you take one single aspirin, you have an antiplatelet ("blood thinning") effect that lasts at least 5 days (50% of your circulating platelets). Bottom line: it doesn't matter what time you take the aspirin. The effect lasts a long time.
Answered 7/30/2019
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