A member asked:

Cymbalta (duloxetine) difficult urination?

8 doctors weighed in across 2 answers

Yes: Cymbalta (duloxetine) is an snri which means it affects both norepinephrine and serotonin. The norepinephrine causes a pseudoantichoinergic effect like caffeine and decongestants and many others that can make it difficult to urinate, esp in older men with prostate problems. It can also help people with bladder frequency. Caffeine and some otc meds are worse.

Answered 2/23/2020

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Dr. Thomas Namey answered

Specializes in Rheumatology

That can occur!: Uncommon, but a definite side effect in some people!

Answered 5/6/2019

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