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Long Branch, NJ
A 17-year-old female asked:

Positive for hla-b27.this procedure rules out the b27:06 & 27:09 alleles which lit suggests arent associated w/ spondyloarthropathies.what this mean?

1 doctor answer1 doctor weighed in
Dr. Aaron Broadwell
Internal Medicine 16 years experience
Spondyloarthritis: Hlab27 is a generic marker that is in 8% of the caucasian population. Many people with diseased called spondyloarthropathies (ankylosing spondylitis, psoriatic arthritis, and crohns/uc related arthritis) will have a positive b27, but not all those with b27 will develop issues (in fact, the vast majority don't). The larger question is are the symptoms consistent with spondyloarthropathy.
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Last updated Nov 17, 2015


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