A member asked:

At 42 yr diagnosis her2 pos br ca , triple pos , node neg . 7 yrs ago . treatment : bilat mass, chemo, herceptin (trastuzumab) \oop . 6 yr a.i. should i stay on a.i ?

6 doctors weighed in across 3 answers
Dr. Stephen Jarrard answered

Specializes in General Surgery

No recommended: Aromatase inhibitors (ai) have not been shown to be effective past five years, and are usually recommended to be stopped at the five year mark.

Answered 1/7/2015

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More info/maybe: This would be easier to answer if the tumor size and grade wear provided. In general, studies in hormone positive breast cancer have shown an advantage to 10 years of tamoxifen over 5 years. Though this cannot be extrapolated to ais, which are considered more effective than tamoxifen, this may be the case. Knowing tumor size and grade would help with prognosis.

Answered 5/9/2014

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Dr. Liawaty Ho answered

Specializes in Hematology and Oncology

Need info/ may be: need information re- stage ( tumor size) and grade etc. discuss with your oncologist in detail. there are 2 studies showing that 10 yrs of tamoxifen is better than 5 years. the MA 17R study hopefully will be able to answer in regard to the use of AI. on switching trials the average length of endocrine therapy is about 7-8 years -tamoxifen 2-3yr then switched to AI x 5 yrs. you need to d/w your onc.

Answered 5/9/2014

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