How do botulinum toxin injections work?

Botox: It paralyse the muscle.

Mechanism of Botox: Botulinum toxin (onabotulinum toxin type a) blocks certain chemical signals that cause muscles to contract. Injections result in paralysis or relaxation of the muscle. The effect is temporary and treatment will need to be repeated in 3- 6 months. Injections are fda approved for treatment of blepharospasm, wrinkles, lazy eye, cervical dystonia, migraines, upper limb spasticity, underarm sweating.

Weakens muscle actio: Botox works to weaken muscle function by blocking the connection between the nerve and the muscle. The Botox action slowly is reversed and eventually the normal muscle action returns.

Transmission block: Botulinum toxins inhibit release of the neurotransmitter, acetylcholine, from peripheral nerve endings thus weakening muscle.