Hi, does grapefruit interfere with celexa (citalopram)?

Yes: Yes, citalopram (celexa) is metabolized by cytochrome p450 3a4 (cyp3a4). Grapefruit juice contains furanocoumarins such as bergamottin which inhibits cyp3a4. So there is an interaction between the two. Hope that answers your question!

Yes, it can: Celexa (citalopram) (and some other medications) are broken down with the help of an enzyme called cyp3a4, whose activity can be blocked by grapefruit juice. So instead of being broken down, more Celexa (citalopram) enters your bloodstream and stays in your body longer.

Grapefruit/Celexa: Yes it can.

Of course: Celexa (citalopram) does interact with the cytochrome P450 complex which is affected by grapefruit.