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A 37-year-old member asked:

Does rheumatic fever cause mitral valve disease?

1 doctor answer4 doctors weighed in
Dr. Martin Raff
Infectious Disease 56 years experience
Yes: One of the features of rheumatic fever is pan-carditis, meaning that all layers of the heart are inflamed. Involvement of the mitral valve occurs 10x more often in women and aortic valve disease 4x more often in men. Quite frequently both the aortic and mitral valves are involved, with the tricuspid next in frequency and the pulmonic the least common. This can result in many complications.

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A 39-year-old member asked:

How does rheumatic fever damage mitral valve?

1 doctor answer3 doctors weighed in
Dr. Omega Edwards
Infectious Disease 19 years experience
Collateral Damage: Our immune system turns on its defenses after exposure to group a strep (strep throat for example). The bacteria is targeted and eliminated. Sometimes the immune system erroneously targets the mitral valve, heart muscle, kidneys and joints. Hence, in trying to eliminate strep collateral damage occurs.

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Last updated Aug 29, 2019

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