A member asked:

Is lou gehrig's disease dominant or recessive?

3 doctors weighed in across 2 answers
Dr. Michael Depietro answered

Specializes in Pulmonary Critical Care

Neither: 90-90% of case of ALS are not inherited, it occurs at random at its cause is not known. In 5-10% of cases there is a familial form of the disease. In these 5-10% of cases it is usually dominant (meaning it is only necessary to have one copy of the defective gene) remember however most of the time it is not inherited at all.

Answered 1/12/2015

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NEITHER: 90% of all cases are sporadic and not of genetic origin. Maybe 10% of cases can be genetic, some associated with front-temporal dementia, 25% associate with superoxide dismutase. The eventual outcome is similar regardless of the above.

Answered 10/11/2012

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