A member asked:

Is fabry disease dominant or recessive? any answer appreciated.

A doctor has provided 1 answer
Dr. Steve Howe answered

Specializes in Thoracic Surgery

X-linked: It is an X-linked inheritance. That means it is found as a mutation on the X chromosome . Males are XY and so one gene mutation in that X chromosome that affects the alpa-galactosidase enzyme will cause the disease. Females are XX and so if one x chromosome has the mutation ,they will often experience a lesser form of Fabry Disease or no symptoms at all.

Answered 12/30/2014

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