I started taking cymbalta (duloxetine) could it cause burning and itching of hands and feet and sour stomach and loose bowls ?

Yes: It can cause all those things, although the itching hands is less common. More info on side effect here: http://www.Webmd.Com/drugs/drug-91491-cymbalta+oral.Aspx?Drugid=91491;drugname=cymbalta+oral;pagenumber=6 also, if you are taking it for depression, be aware that medication alone is not optimal treatment. Consider psychotherapy, or psychotherapy + meds.