What is the relationship between lipoprotein in the blood stream and heart disease?

Lipoproteins and CAD: Some types of lipoproteins which are carried in the blood can lead to fatty deposits in the arteries and these fat deposits or fatty streaks can lead to narrowing in the arteries. This narrowing causes decreased blood flow and can occur in the heart, brain, intestines or anywhere. These narrowings in the heart can cause angina, or chest pain, or a heart attack due to complete blockage.

LDL Drives HDL Stops: Ldl (i.e. Smallest which are still lower density than water), when not at low concentrations, drive atherosclerosis. Hdl (i.e. Even smaller & higher density than water), if the particles remove fats from cells overloaded with intracellular fat before they die in the walls of arteries, help prevent atherosclerosis. Ldl is not cholesterol. Hdl is not cholesterol. Ldl-c does not reveal ldl-p, etc.

Atherosclerosis: Following entry into the artery wall low LDL particles directly promote development of atherosclerosis ("hardening of the arteries") and increase risk for heart attack and stroke. Hdl particles work in several ways to decrease atherosclerosis and cardiovascular risk. As a result, increased numbers of LDL particles, as well as decreased numbers of HDL particles, are risk factors for heart disease.