A member asked:

My mum has non alcoholic fatty liver disease & just been diagnosis with type2 diabetes - her ferritin has been very high - could hemochromatosis be cause?

4 doctors weighed in across 2 answers

May need liverbiopsy: Although blood testing (measurement of iron studies and hfe assay) combined with family history can be very suggestive, a liver biopsy with iron staining clinches a diagnosis of hemochromatosis and distinguishes it from other iron overload diseases. Ferritin by the way can also be reactive or a secondary phenomenon.

Answered 11/1/2015

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Could be: Liver disease and diabetes are common manifestations of hemochromatosis. It's important to remember that ferritin is an acute phase reactant and any inflammatory process can lead to increased values. Non-alcoholic steatohepatitis (nash) can lead to elevations in ferritin.

Answered 9/29/2016

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