A member asked:

Can using klonopin (clonazepam) 2.0 and cardizem cd 120 lead to cns depression?

4 doctors weighed in across 2 answers

Minimally, but yes: Diltiazem may increase the blood levels and effects of clonazepam. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience increased side effects or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Source: www.Drugs.Com.

Answered 4/7/2016

4.3k views

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Potentiation of: Diltiazem can and does cause potentiation of benzodiazipines, but i doubt at the dose described will cause CNS depression.

Answered 4/7/2016

4.3k views

Thank

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