See below: The exact cause of reye's syndrome isn't known but an important risk factor is taking Aspirin during certain viral illnesses, particularly chickenpox and flu in children and teenagers, especially if they have a genetic predisposition (abnormal fatty acid metabolism). Aspirin is largely metabolized a day or so after the last dose (the effect on clotting lasts a week).
Answered 6/24/2014
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Age/illness related: The era of Reye Syndrome peaked in the late 70's in kids after flu or chickenpox.It began to decline when we quit using aspirin products with kids. It hit mostly school age kids under 16.Today we don't use aspirin like products in kids under 16.
Answered 4/24/2016
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