A member asked:

I took bupropion for five years or so, went off for 7 months. how long will it take to get back into my system and start working?

5 doctors weighed in across 2 answers
Dr. Robert Grieco answered

Specializes in Family Medicine

2-6 else: Usually bupropion is given in 1/2 dose (150mg) for week then full dose. Full blood level in a few days after that bit the improvement/ effects can take much longer depending on what is being treated. For depression it is not as fast as we would like. Other people might notice improvement in apathy before the patient "feels better" but the full effect can be > 6wks. Previous success = good.

Answered 3/24/2014

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Varies: May notice a difference within a week however can take 4-6 weeks to take full effect.

Answered 4/9/2016

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