U.S. doctors online nowAsk doctors free
A 29-year-old female asked:

Is it okay to take nyquil for cold along with 50 mg trazodone for insomnia? i am also on wellbutrin (bupropion) xl 300 mg/day for 1.5 years.

1 doctor answer4 doctors weighed in
Dr. Johanna Fricke
Pediatrics - Developmental and Behavioral 51 years experience
No. Dextromethorphan: Dextromethorphan + Trazadone can cause a serious condition, Serotonin Syndrome. Doxylamine + Trazadone can cause dizziness & drowsiness. See: www.drugs.com/interactions-check.php?drug_list=2228-0,55-1943&types[]=major&types[]=minor&types[]=moderate&types[]=food. Always ask your doctor or pharmacist before adding any vitamin, herb, OTC or prescription drug to a psychotropic medication.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Nov 9, 2020


Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.