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A 29-year-old female asked:

Is it okay to take nyquil for cold along with 50 mg trazodone for insomnia? i am also on wellbutrin (bupropion) xl 300 mg/day for 1.5 years.

1 doctor answer4 doctors weighed in
Dr. Johanna Fricke
Pediatrics - Developmental and Behavioral 51 years experience
No. Dextromethorphan: Dextromethorphan + Trazadone can cause a serious condition, Serotonin Syndrome. Doxylamine + Trazadone can cause dizziness & drowsiness. See: www.drugs.com/interactions-check.php?drug_list=2228-0,55-1943&types[]=major&types[]=minor&types[]=moderate&types[]=food. Always ask your doctor or pharmacist before adding any vitamin, herb, OTC or prescription drug to a psychotropic medication.
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Last updated Nov 9, 2020

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