A member asked:

Speckled ana, raised esr, swollen painful knee and ankle, pains in feet and toes worse morning and night, headaches, lethargy, pins and needles hands?

A doctor has provided 1 answer

Neuropathy: The numbness and tingling are symptoms of a possible neuropathy. The ESR is suggestive of an inflammatory disorder, which may depend how high the level is. There are several more common inflammatory disorders that can cause this constellation of syndromes and a rheumatologist and neurologist should be involved in your care.

Answered 6/10/2014

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