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A 20-year-old female asked:

Starting generic zoloft (sertraline). worried about side effects-nausea and upset stomach. is it ok to take promethazine for nausea/vomiting and pepto for stomach?

2 doctor answers4 doctors weighed in
Dr. Oscar Novick
Pediatrics 58 years experience
Nausea: Taking zoloft (sertraline) and Promethazine together may increase serotonin levels which can cause heart problems. Try taking Promethazine a half hour before zoloft (sertraline) to ameliorate side effects.
Dr. Linda Callaghan
Addiction Medicine 53 years experience
Yes.: Take the zoloft (sertraline) after a meal and the stomach discomfort may not occur. However, if they do, it would be alright to take either Promethazine or peptobismol.

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Last updated Jun 13, 2018

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