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A 20-year-old female asked:

Starting generic zoloft (sertraline). worried about side effects-nausea and upset stomach. is it ok to take promethazine for nausea/vomiting and pepto for stomach?

2 doctor answers4 doctors weighed in
Dr. Oscar Novick
Pediatrics 59 years experience
Nausea: Taking zoloft (sertraline) and Promethazine together may increase serotonin levels which can cause heart problems. Try taking Promethazine a half hour before zoloft (sertraline) to ameliorate side effects.
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Dr. Linda Callaghan
Addiction Medicine 54 years experience
Yes.: Take the zoloft (sertraline) after a meal and the stomach discomfort may not occur. However, if they do, it would be alright to take either Promethazine or peptobismol.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Jun 13, 2018

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