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A 40-year-old female asked:

How do you know if you'll have a bad reaction to general anaesthetics? had conscious sedation, epidural and 2 spinal blocks which seemed to last long no family history of bad reactions that i know of.

2 doctor answers2 doctors weighed in
Dr. Nestor Del rosario
Addiction Medicine 34 years experience
Reaction: That is being sought preoperatively is that of neuroleptic malignant syndrome causing high fever, abnormal muscle contractions or even seizures, and yes, it does run in the family.
Dr. Karen Sibert
Anesthesiology 39 years experience
Malignant hyperthermia is a severe reaction to GA that runs in families. Neuroleptic malignant syndrome is a rare but severe reaction to certain types of drugs used in psychiatry, not in anesthesia.
Feb 22, 2014
Dr. Karen Sibert
Anesthesiology 39 years experience
Unlikely!: Most common unpleasant side effect of general anesthesia (ga) is nausea; today we have good meds to minimize that. Severe or allergic reactions to drugs used in ga are very rare, and we are trained to recognize and treat them. There's no way to know in advance. But if no one in your family has had a problem, you probably won't. Talk to your physician anesthesiologist before surgery. Good luck!

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Last updated Feb 22, 2014

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