A member asked:

Valerian increases gaba. it helped me with my anxiety when taken daily (500mg) but once stopped i experienced worsened anxiety, now what? go back?

A doctor has provided 1 answer
Dr. Ward Dean answered

Specializes in Holistic Medicine

Go back to valerian: The active ingredient in valerian is valerolactone. Gamma hydroxybutyric acid (ghb) -- the notorious "date rape drug" --is, in actuality, the safest, most non-toxic, non-habit-forming sleep-inducing substance known. Gbl (gamma butyrolactone) is converted by lactonase in the blood to ghb. I believe valerolactone in valerian is converted to ghb, an effective anti-depressant/anti-anxiety agent.

Answered 2/21/2014

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