Sinemet (carbidopa and levodopa) dose: A typical starting dose for sinemet (carbidopa and levodopa) is 25/100 once or twice a day. A maintenance dose will likely end up being three times a day, however if you start too fast it can cause nausea and other gastrointestinal symptoms.
Answered 2/20/2014
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Small dose: In view of the reactions at the start (mostly gastrointestinal ) it is best to start with a very small dose e.g. Half a tablet of 25/100 and very gradually increase by increments on a daily basis even people tolerating much bigger dosages later should start slowly.
Answered 2/20/2014
4.4k views
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