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A member asked:
Why is sinemet (carbidopa and levodopa) cr is inferior to regular sinement in terms of strength even though they carry the same mg in terms of dose for parkinsons?
4 doctors weighed in across 2 answers
Time release: Time released or controlled release Sinemet (carbidopa and levodopa) is not inferior- the drug is just released more slowly into the system.
Answered 8/22/2014
3.8k views
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Different timing: CR is sustained release. Regular lasts only a few hours and tends to have more peaks and troughs. One can use both. Regular is given 3 to 4 times a day.
Answered 11/28/2017
3.8k views
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