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Meriden, CT
A 23-year-old female asked:

what are the best antiemetics for cisplatin vomiting. would phenergan (promethazine) work at all? it's to my knowledge that cisplatin is the most emetogenic chemos.

2 doctor answers2 doctors weighed in
Dr. Marwan Akasheh
Hematology and Oncology 39 years experience
Chemotherapy: Aprepitant is the best drug in addition to dexamethasone.
Dr. Costantine Albany
Medical Oncology 19 years experience
Prevention: The best treatment for cisplatin induced nausea and vomiting is to prevent in the first place. Before cisplatin is given you should get a lot of fluids for hydration, then Dexamethasone, 5HT3 antagonist such as Zofran and NK1 antagonist such as aprepitant. together this combination with prevent nausea and vomiting. if still sick Compazine, (prochlorperazine) Zofran, etc can help as needed. Remember hydration!

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Last updated Aug 21, 2015
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