A member asked:

Lamotrigine and missed period? five days late. how common is the medicine w its effect of hormonal changes?

A doctor has provided 1 answer
Dr. Rhonda Simons answered

Specializes in Family Medicine

Most importantly: About Lamotrigine is it's effect on folate metabolism. If you are mthfr 677 or 1298 positive, and you doc has given you "regular" folic acid, you likely can't use it. 84% of us population has this defect. You need l-methylfolate, b6, ; B12 to keep the biochemical circle going right and supplying you with serotonin, dopamine, nor-epi ; melatonin. Mthfr also effects fertility, so important to treat.

Answered 6/26/2014

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