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A 42-year-old member asked:

can you tell me how could neostigmine works and its mechanics?

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Dr. Djamchid Lotfi
Neurology 58 years experience
Yes!: acetyl choline is the neurotransmitter across the neuromuscular junction. It is removed by hydrolysis. Neostimine slows this process and therefore increases acetylcholine concentration at this site

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A 39-year-old member asked:

How can neostigmine works and its mechanics?

1 doctor answer1 doctor weighed in
Dr. Alexander Bankov
Anesthesiology 37 years experience
Anticholinesterase: neostigmine inhibits the activity of the enzyme responsible for breaking down the acetylcholine, the ubiquitous neurotranmitter. In anesthesia it is commonly used to reverse action of curare-like medications that cause muscle relaxation/ temporary paralysis necessary to facilitate surgery. Hope that helps

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Last updated Oct 7, 2014
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