How are depression and despair different?

Despair / Depression: Despair is a complete and utter loss of hope. Despair can be a symptom of clinical depression. Depressive sx's may include low mood, irritability, anger, ^ or v sleep, change in appetite, feelings of helplessness or hopelessness, v energy, v self-esteem, feelings of guilt. V motivation, absence of joy, v concentration, v memory ; suicidal thoughts.