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A 49-year-old member asked:

can you tell me about drug interactions of oxycodone/hydrocodone?

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Dr. Alan Wartenberg
A Verified Doctor answered
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Very few: In terms of increasing or reducing the levels/ effectiveness of other drugs, these opioids have few if any drug interactions. However, for any other drug which can be a central nervous system depressant, like alcohol, sedatives, tranquillizers, antihistamines and many other drugs, the combination can cause increased potential for respiratory depression, fainting, sedation, accidents, falling.

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Last updated Feb 1, 2014

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