They're different: They're apples and oranges! Lasix (furosemide) is a potent diuretic. Spironolactone is a weak diuretic that is usually used with Furosemide or hydrochlorothiazide because it helps counteract the loss by the kidneys of potassium those diuretics cause. Moreover, it counteracts a hormone that make heart failure worse and that effect is independent of its diuretic effect.
Answered 5/27/2019
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