A member asked:

Will a relatively large dose of caffeine bring out hives in someone prone to them? i get 1 or 2 after taking tyl w caff, but not w plain tyle tabs.

A doctor has provided 1 answer
Dr. John Chiu answered

Unusual: I am not aware of anyone being allergic to caffeine. However if you have a condition known as cholinergic urticaria (small, red, and itchy bumps lasting for a few hours), one can postulate that the heightened stress response from excessive caffeine could trigger cholinergic urticaria. If the typenol with caffeien is in a capsule form, gelatin allergy is a consideration. Fillers in t/cod?

Answered 6/1/2015

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