In context of cryofibrinogenemia, lupus-type ctd and adrenal insufficiency, what could cause increase in gi symptoms, nausea, and vomiting with adrenal crisis, when estrogen/progestin drugs are taken?

Need more info: Cryofibrinogenemia is a complex illness with many side effects. You must discuss this in depth with your treating physician.

Cortisol deficiency : With true adrenal insufficiency diagnosed by an endocrinologist, one would need to be taking cortisol replacement therapy. Nausea, abdominal pain, vomiting and weight loss are classic symptoms of adrenal insufficiency which estrogen and Progesterone replacement don't address. Many with primary adrenal insufficiency also look like they have a deep tan.